Mississippi 

 Why you annoy me:

• You are probably the dirtiest state I’ve ever been to.
• Your interstate rest area bathrooms have trough style urinals and no door on the stalls.  This is all very classy and makes for a fun bathroom experience.  Add a bus full of an Asian tour group and hilarity will ensue.
• Louisiana would be just as bad but at least they have New Orleans to mitigate their suckage.  Alabama too sucks, but at least their country folk have a modicum of self-respect.
• Your state is dead last in education in the country.  Granted, someone has to be dead last every year, but you think you’d try to not be that one EVERY year.
• Your state persisted in Jim Crow and racist practices significantly longer than other Southern states.
• Your state takes in significantly more federal spending than it pays out in taxes.  Then you have the nerve to vote Republican because you are for “lower taxes and less government.”  Your whole fucking swamp-trash state is nothing but a state of beggars with their hands out and you have the gall to vote Republican.

 Possible mitigating factors:

• Your people, while annoying hypocritical idiots, realize that they are swamp trash and thus act accordingly humble.  Compare that to people from Georgia or Texas who are nearly as trashy, but significantly louder.
• At first I thought Mark Twain might be from your state, which would be huge in your favor, but upon further investigation I found he was from Missouri.  You officially suck.